ACTOS Reviews (PIOGLITAZONE HYDROCHLORIDE)

Average Rating: 1.7 (361 Ratings)

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 Type: Rx Drug

  

ACTOS  (PIOGLITAZONE HYDROCHLORIDE):  Pioglitazone is a diabetes drug (thiazolidinedione-type, also called "glitazones") used along with a proper diet and exercise program to control high blood sugar in patients with type 2 diabetes. It works by helping to restore your body's proper response to insulin, thereby lowering your blood sugar. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Proper control of diabetes may also lessen your risk of a heart attack or stroke. Pioglitazone is used either alone or in combination with other diabetes medications (such as metformin or a sulfonylurea such as glyburide). Talk to your doctor about the risks and benefits of pioglitazone.   FDA Approval Date: 1999-07-15 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR ACTOSCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  High blood sugar Suddenly my legs are itching non stop. As of yesterday I have been light headed, completely exhausted, and constantly shitting myself with no relief. And I can NOT get warm. I am NEVER COLD NORMALLY. And even though I am hungry, I try to Eat and get nauseous. Stay away from this crap. The being cold is an indication of this crap causing kidney problems. F 52 2 weeks
30 mg 1X day
2/16/2022
 1  Type 2 diabetes Feet and legs swelling short of breath lower back ache and lots of weight gain . F 74 50 days
15 mg
10/4/2019
 1  Type 2 diabetic Swelling of the ankles, feet and legs. Pain across the top of both my feet. I'm not able to wear certain tennis shoes in regard to the pain. I'm generally a happy go lucky person and lately I have been depressed. Some days I feel as if I won't live to see another day. I never had this issue with Glipized and metformin. To this day I don't know why the doctor took me off Glipized. I understand the numbers showing good but what about the side effects ppl are complaining about. We are not ginney pigs. I asked for something else my doctor told me no. I will stop this actos on my own and find another doctor that will not just see me but hear me. F 44 3 months
30mg
5/15/2017
Email
 1  High A1c Intense pain in right shoulder.started on.day 2. X-rays showed nothing. Stopped drug and still have pain 4 days later Then, pain shifted to right shoulder and pain in left stopped. Hoping it all eventually Stops. Awful side effect although it was.working well for blood sugar levels. M 47 10 days
11/20/2016
 1  decrease blood sugar and A1C My endo has been trying to find a drug that will minimize my A1C and decrease my insulin requirement. I'd rather stick with the insulin than to take this drug. I stopped after the 7th day of taking these: nausea, vomiting of bile, no appetite, shortness of breath, chest tightness, chills, dizziness, pain under shoulder blades(right then left), varying degrees of anxiety and everyone's favorite: restless leg syndrome. These side effects are nearly gone after 72 hours since my last dose. After this nasty reaction, I am highly unwilling to try a lower dose. The insulin savings weren't good enough to treat the side effects. My previous PCP, an ARNP, had been a diabetic educator before switching to family practice. After the reactions that I had to metformin, Januvia and Byetta, she opted to skip trialling other drugs and put me on insulin. She felt that the rest of the various meds available (including Actos) carried too much chance of weight gain and other unpleasant side effects to even try, especially given my history of rapidly rejecting anything my body found objectionable. F 50 10 days
30 mg
8/30/2016
 4  Dysmetabolic Syndrome Leg cramps, some edema of calves & feet @ higher dosage, abdominal pain @ higher dosage I started this medication @ a higher dosage & had problems, so began to decrease until the complications became less or disappeared. Otherwise, it has helped me feel much better & has worked to get my condition under control. F 52 6 months
7.5mg 1X day
7/22/2016
 1  Type 2 diabetes Gross weight gain, constant tiredness, swelling in ankles I told my endocrinologist I am going off Actos and will never touch it again. It's horrible. It's banned in Europe although my doctor pooh-poohed that. I gained weight steadily, a pound a month without relief, even with lots of exercise and good diet. I already take glimeperide (about 3 mg per day average) and will go on Byetta if necessary. But after just three weeks off Actos, I am starting to feel better, have way more energy, and am starting to slowly lose a little weight. I think I can get back to normal weight in a few months (faster if I go on Byetta). Actos is evil incarnate. How can gross weight gain possibly be good for anyone let alone a diabetic? My doctor could care less so now I do the research and tell him what I want to take. M 67 18 months
45mg 1X day
5/23/2016
 1  Type 2 diabetes Severe muscle and joint pain, weight gain and teeth became soft and brittle. F 54 3 months
30mg
5/12/2016
Email
 1  Type2 diabetes Face and tongue very swollen can't breathe hive and sore throat fever cold sweats. Ringing loud noises in left ear swollen eyes and bottom eyelids turned out. Direah very sick and muscles twitching .still days later knots on back of tongue choking feeling I have a lot of allergies but was really scared. So be careful F 63 3 days
45
4/21/2016
 1  Type2 diabetes Face and tongue very swollen can't breathe hive and sore throat fever cold sweats. Ringing loud noises in left ear swollen eyes and bottom eyelids turned out. Direah very sick and muscles twitching .still days later knots on back of tongue choking feeling I have a lot of allergies but was really scared. So be careful F 63 3 days
45
4/21/2016
 1  Type 2! Was on Avandemet. Before Bug time ankle swelling Took 3.5 years to screw me up. Weight gain started year 2 M 73 4 years
15
3/7/2016
 1  Type 2diabetes Chest pain, mood swings, dizzy, sleepy, swelling. F 53 7 days
12/21/2015
 1  Diabetes Being checked for bladder cancer after getting symptoms . Anyone else had symptoms ? F 50 1 days
45mg
8/20/2015
Email
 1  Diabetes Type II My leg become very itchy and when I scratched the skin breaks. My back itches and no topical ointment can provide me any relief. Lumps develops and when I press it, liquid oozes out of them. I have otherwise been taking Actos for my Diabetes for many years since I was 55 and now I am 70. Recently, I could not find the source of the itch. Now I do. I stop taking it and my itches are being relieved. M 70
45 1X day
7/14/2015
Email
 1  Type 2 diabetes Ankle swelling is the worst, but also causes lower legs and feet to swell. I have been on it for approximately 6 months. It won't let me change that field i have taken myself off of Actos x 4 days now. The swelling is much less. My glucose levels are only slightly elevated. I have never felt like it was very effective at helping lower my glucose levels. I was on Victoza, which controlled my levels very nicely. My A1c's were between 6.2 and 6.4. It kept me from being hungry; However, it was causing severe constipation and mid abdominal pain, so the Dr. Took me off of it and put me on Actos 30 mg. now my A1c is up to 7.6! Talk about discouraging! F 60 10 months
30 mg
5/15/2015
Email
 3  type 2 diabetes Swollen feet, ankles and legs-- extreme Worked very well; sad about side effects- M 58 2 years
30 mg
5/14/2015
Email
 4  Type 2 diabetes After being on it for a year I've started with pitting edema in my lower legs,feet and ankles and severe muscle pain. The top of my foot has been so swollen that it hurts to move my toes. I hate the side effects that are presenting because it has controlled my blood sugars. Glucophage caused to many stomach issues and didn't control my levels like Actos has.i hope to find something that works without crazy side effects. Byetta made me extremely sick. I do take Bydureon. F 44 1 years
45mg
1/20/2015
Email
 1  Diabetes Type II At the Beginning this drug was wonderful, few side effects, in two weeks bring my levels down to 90-110, before actos i was 190-210, was eating light and doing my walkings, on weekends diet was a bit relaxed. But in the 4th and 5th month, caos started, blood pressure was up and dow, start to feeling dizzy, edema on feet, 30 pounds weight gain, body, hands, and feet were itching all the time, Panic Attacks, i had the feeling to run away, very bad time, the last month, i had pain in legs, back and arms. this is poison, this will kill you, after a week i quit Actos, i felt like 10 years younger, happy, no pain, no edema, and already lost 10 pounds. Donīt take this drug, is living hell M 50 6 months
30 MG 1X day
11/11/2014
 1  Diabetes Very swollen legs!!! How long does it take to resolve after stopping the actos? M 70 2 years
30
10/29/2014
Email
 1  Type 2 Diabetes Hypoglycemia. Legs swelling/edema. Weight gain (8 lbs in 1 week) even with diet and regular high intensity exercise. F 28 1 months
15
4/12/2014
  

ACTOS  (PIOGLITAZONE HYDROCHLORIDE):  Pioglitazone is a diabetes drug (thiazolidinedione-type, also called "glitazones") used along with a proper diet and exercise program to control high blood sugar in patients with type 2 diabetes. It works by helping to restore your body's proper response to insulin, thereby lowering your blood sugar. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Proper control of diabetes may also lessen your risk of a heart attack or stroke. Pioglitazone is used either alone or in combination with other diabetes medications (such as metformin or a sulfonylurea such as glyburide). Talk to your doctor about the risks and benefits of pioglitazone.   FDA Approval Date: 1999-07-15 (Sources: U.S. Centers for Medicare Services, FDA)

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