NALTREXONE HCL Reviews (NALTREXONE HYDROCHLORIDE)

Average Rating: 3.7 (44 Ratings)

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 OPIATE ANTAGONIST

 Type: Rx Drug

  

NALTREXONE HCL  (NALTREXONE HYDROCHLORIDE):  This medication is used to prevent people who have been addicted to certain drugs (opiates) from taking them again. It is used as part of a complete treatment program for drug abuse (e.g., compliance monitoring, counseling, behavioral contract, lifestyle changes). This medication must not be used in people currently taking opiates, including methadone. Doing so can cause sudden withdrawal symptoms. Naltrexone belongs to a class of drugs known as opiate antagonists. It works in the brain to prevent opiate effects (e.g., feelings of well-being, pain relief). It also decreases the desire to take opiates. This medication is also used to treat alcohol abuse. It can help people drink less alcohol or stop drinking altogether. It also decreases the desire to drink alcohol when used with a treatment program that includes counseling, support, and lifestyle changes.   FDA Approval Date: 1998-05-08 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on NALTREXONE HCL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR NALTREXONE HCLCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  heroin addict i do not have the euphoria in me. M 30 4 years
4/15/2003
Email
 5  Fibromyalgia Tiredness at 1st, but went away in a few weeks This is my miracle drug. I was taking tramadol before which helped, but I still had mild pain. Before I took anything my pain was so bad. Before I knew I had fibro I toughed out the pain for 3 years. I couldnt lift my arms past my waist and in order to roll over in bed I had to lift my arms slowly to roll over. I would leave 2 hours before work and stop every few minutes to rest. Note I live 10 to less than 15 min from work. Lifting a pencil was so painful. I decided enough is enough and saw many many doctors before I found 2 that helped me diagnose my fibro. And maybe frozen shoulder they said. I see a pain mgmt doctor now who prescribed me the low dose naltrexone. It's my miracle drug. It gave me my life back. I work as a pharmacy tech and other patients also agree that it's working for them. One said she was just starting it and didnt like the side effects. I told her to give it a a few more days and now she said she was glad she did. They milded down. I see patients who are on continuous use opioids and often wonder if this would work for them.. I hope the FDA is looking into this drug as possible approving it. At least making doctors more aware of it to try for their patients. Getting them off opiods.. I read it can also help with crohns, which I also have. I'm not sure on how it can help with that. My crohns is under control as of today. It would be neat if it helped with that. F 40 3 years
4.5mg 1X day
1/1/2021
 4  Ulcerative Colitis Taking from 3-4.5 mg per night before bed. This is called low dose naltrexone and is used for things like ulcerative colitis, cancer, and a lot of other stuff at this low dose. It helps your overall health but I came on here to warn people that is does have similar side effect to steroids in that it can make you enraged to a psycotic level where you want to beat the living ____ out of someone. Be aware of this and leave the room if you get in an argument with someone otherwise you literally will not care and will say a whole lot of _____ you would normally not say or care to say. I use a 50mg tablet and dissolve it in 50ml of distilled water in a tincture then drip 3-4.5ml of that after shaking it so it may not be exact all the time but I am too cheap and lazy to order more exact ways to measure it. You have to get it illegally if you want to use it for ulcerative colitis or find some expensive alternative doctor to prescribe it (safest idea), since my bastard GI refused to prescribe it to me for UC, all he would prescribe is steroid prednisone. I use the naltima brand or the nodict brand, don't sense any difference between them, both are naltrexone. M 46 3 years
4 1X day
12/8/2015
 5  Alcoholism Exhaustion, nausea first few days. This drug changed my life. I began it in early sobriety and haven't stopped it. Once I began to take it my cravings went away. I do skip it sometimes now and I have no cravings. I believe this medicine saved my life! M 36 2 years
50mg 1X day
10/27/2021
Email
 5  Alcoholism Exhaustion in beginning , nausea, This medication saved my life along with 12 step fellowship helped me get abs stay sober still on it all these years later F 36 2 years
50mg 1X day
3/27/2022
Email
 3  Alcohol addiction Jitty legs, nightmares, decreased libido. Has not totally diminished desire to drink. M 35 1 years
1/3/2005
 5  Hepatitis c Early sleep disturbances but they passed after a week. Am taking 3 mg. Low Dose Naltrexone for Hepatitis C, which I started in Feb. 2009. My viral load dropped from over a million to 18,000 and my liver function tests are normal. Many other folks with various forms of Hepatitis are also having great results - at very low doses. Must be made at compounding pharmacy!!! F 57 9 months
11/22/2009
Email
 5  Multiple Sclerosis The first week, I think that I got less sleep, but when I got up in the morning, I felt so good that it did not matter. I think my dreams were more fun and memorable for the first week too. The lack of major side effects is not the point with Low Dose Naltrexone. This drug has given me my life back. By nine years after diagnosis, I was losing some mobility, had horrible mental fog, and fatigue that was truly debilitating. Within weeks of starting LDN, I felt like I could almost believe that I no longer had Multiple Sclerosis. I think that the worst thing is that it seems too good to be true and people hesitate to try it with such glowing reports. There are not side effects and no down side. At $30 per month, there is no harm and the potential for good is enormous. F 62 7 months
11/9/2009
 5  MS Absolutely none. Except vivid dreams the first week. In time, this will be seen as a wonder drug in the low dose. Patent expired, and thus, the drug companies have no incentive to help get this out. It is all word of mouth or the net. But, awareness is growing. To date, there are over 25 serious conditions which this drug helps. It has not helped me walk better with my MS, but it has helped with other things such as brain fog, fatigue, and even cognition. Beware of Nay sayers. They have an agenda. M 59 7 months
4.5 mg 1X day
4/16/2010
Email
 5  Alcohol dependence Early side effects of dizziness and nausea, but that passes in 2 weeks. I was a heavy drinker from the time I was 20 or so until I was 29. got Naltrexone 50mg. If I wasn't at work or asleep I was drinking. As hard as it was, I stayed sober for 6 whole days before I started the medicine. From the moment I took the first pill, it. was. gone. I was no longer an alcoholic. They say that once a drunk always a drunk, I'm living proof that is false. I took Naltrexone for 6 months and never looked back. Naltrexone changed and saved my life. M 40 6 months
50 1X day
10/11/2019
 5  Crohn's disease Vivid dreaming for a week I'm taking LOW DOSE NALTREXONE (LDN) for Crohn's disease. It's definitely helping with the symptoms after immunosuppressants stopped working. It ALSO cleared up my arthritis pain. My wife noted that my arthritis pain was gone and she started taking it for her arthritis pain. Her arthritis pain is now gone also. I highly recommend LDN. M 67 5 months
6/13/2009
 5  fibromyalgia, chronic fatigue Wake up briefly during the night, but fall right back to sleep. After the first dose of LDN I had increased energy & I still have a more normal energy level; fatigue is 95% gone. Pain relief came after about 6 wks. and has been reduced about 75%. This med has given me back my life. No thyroid issues while taking Armour Thyroid. F 65 5 months
3 mg 1X day
8/23/2012
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 3  Irritable bowel syndrome It helped with my IBS and sleep. But it made me lazy and unmotivated during the day. When I stopped taking it I found I slept very poorly. Prior to starting on it I slept fine. I went off it for 2 months but my sleep never returned to normal so I went back on it. M 55 5 months
5 mg 1X day
8/16/2020
 2  arthritis None. My doctor and the low-dose naltrexone website implied that LDN might help arthritis as it is an auto-immune disease. I tried 3.0 mg for five months and then 4.5 mg for five months but saw no change in symptoms. I saw no change after quitting either. M 60 5 months
3.0 mg 1X day
10/14/2010
 4  Self-Injury While Sleeping Feeling like there were knots in my stomach I didn't have problems with it. It helped some. F 26 4 months
6/7/2007
 5  Fibromyalgia Energy, spaciness, tired after meals I tried naltrexone at a low dose of 4.5 mg dose years ago, and it had no effect on my pain levels. But at a higher dose (I started with 24.5 mg and now take 50 mg) it is extraordinarily effective. I'm thrilled with this result, but I worry about the long-term effects, so I do not plan to take it indefinitely. The side effects - energy, a spacey feeling - I find pleasant. But this also makes me worry that perhaps this is just another painkiller, and that I'll build up a tolerance and be worse off when I try to wean myself off it. It's promoted as safer and non-addictive, but not enough is known about it yet for those claims to be trusted. It perplexes me that naltrexone is an opioid antagonist, but it feels slightly like an opioid to me. So I'm trilled to have relief from the pain, but I proceed with caution. F 58 3 months
24.5 mg 1X day
11/25/2020
Email
 4  alchohol abuse super tired, that's it. It works, it gets rid of jitters and sweats and decreases craving F 33 3 months
3/11/2007
 1  Opiate abuse Dysphoria, depression and suicidal. Would not encourage anyone to use this as the side effects outweighed any benefits. M 41 3 months
3/10/2008
 5  Crohn's Disease Sleep disturbance initially. Stirred up candida giving me flu-like symptoms but an anti-candida diet has settled these down. The low Dose Naltrexone has certainly improved my symptoms. I was in a flare when I started. Brain fog lifted immediately; number of bowel motions halved and nausea lifted in first week. Tummy pains decreased significantly and weight stabilised. My energy levels fluctuate but there is some improvement. The flare I was in stopped and I have been able to reduce my prednisone from 10mg to 8mg in the 2 months I have been on LDN.I'm so pleased to be off 6-MP and reduce my prednisone to levels I haven't been able to do for over 10 years. I'm not completely symptom-free but LDN has worked without any of the awful side-effects other drugs have. This is a terrific med. F 54 2 months
4.5mg 1X day
5/5/2010
 4  Fibromyalgia, PTSD, Chronic Fatigue The first day I had so much energy and mental focus. I got more done than I have in years. Unfortunately, that did not continue; but I still have substantially more energy and mental focus than before. No negative side effects - hard to believe; but true. I experience more pain free days, increased energy, and lovely dreams. My sleep is better and longer. I used to sleep fitfully, in pain, with tense muscles and would awaken too early feeling like I had been in a battle all night. Now I sleep longer and deeper. I take less Advil. I think the hypervigilence (jumpiness) and disocciation that accompany my PTSD are much improved. I began taking this in the morning and moved to night time dosing. I took the first one on a Saturday morning and reorganized cabinets, shelves and closets all day without pain or fatigue. IF that had continued I would say that it was wonderful but not totally practical for my body. Put the first dose to good use in case that happens for you! Clean closets for the fist time in several years. Ahhhhhh....:-) F 44 2 months
3 1X day
12/18/2010
  

NALTREXONE HCL  (NALTREXONE HYDROCHLORIDE):  This medication is used to prevent people who have been addicted to certain drugs (opiates) from taking them again. It is used as part of a complete treatment program for drug abuse (e.g., compliance monitoring, counseling, behavioral contract, lifestyle changes). This medication must not be used in people currently taking opiates, including methadone. Doing so can cause sudden withdrawal symptoms. Naltrexone belongs to a class of drugs known as opiate antagonists. It works in the brain to prevent opiate effects (e.g., feelings of well-being, pain relief). It also decreases the desire to take opiates. This medication is also used to treat alcohol abuse. It can help people drink less alcohol or stop drinking altogether. It also decreases the desire to drink alcohol when used with a treatment program that includes counseling, support, and lifestyle changes.   FDA Approval Date: 1998-05-08 (Sources: U.S. Centers for Medicare Services, FDA)

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