MIRTAZAPINE Reviews (MIRTAZAPINE)

Average Rating: 2.4 (45 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

MIRTAZAPINE  (MIRTAZAPINE):  Mirtazapine is used to treat depression. It improves mood and feelings of well-being. Mirtazapine is an antidepressant that works by restoring the balance of natural chemicals (neurotransmitters) in the brain.   FDA Approval Date: 2005-08-31 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by length of time drug was taken from shortest to longest duration (reviews with no time reported listed first).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on MIRTAZAPINE: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR MIRTAZAPINECOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Depression Bloating, weight gain, insatiable appetite, mood swings, headaches daily, bad taste in mouth, bugs crawling under my skin, nausea, vomiting, diarrhea. Nightmare so bad that I became an insomniac. Skin felt like I was on fire Horrible horrible medication wouldn't recommend it because of the side effects and never mind withdrawal! Yikes! I was bedridden for three weeks only got up to have a bit of soup when I could handle it or going to the bathroom! Sometimes it would be coming out both ends! F 42 100 days
30 1X day
10/18/2020
Email
 1  Depression and insomnia Was on 15mg but still wasn’t sleeping and still feeling depressed. Was put on 30mg but now I’m having tingling and numbness in my hands, am having lots of trouble waking up, even after over 8 hours sleep, feel foggy headed most of the next day, plus very irritable. Never feel full no matter how much I eat, whereas before I was on it, I hardly ate anything. I’ve put on over 1 stone in 5 weeks!!! Need to try and change on to something else, I can’t handle these side effects F 35 1 weeks
30mg
4/3/2020
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 2  Axiety Started on 15mg dizzy. Wanted off but doctor took me to 30mg Thanksgiving morning my head felt numb then that sat my left side of head felt numb. Constant dizzy i went to minute clinic and the checked my ears not enough fluid in ears to cause dizzy so i called doctor on monday so i. Said i want off this medicine first i would of thought she would of started me to taper off first well i was scheduled to take my 15mg at 8pm i didnt and had chest pains from 8pm until the next day when i took a clozepam .25mg so now i have chest palpatations but i take a clozepam to relax me. I take the remeron usually at 7 or 8pm and i dont fall asleep until 12 or so i guess u r suppose to eat alot on this medicine. Well i dont. Getting ready to switch doctors. Constant dizzy and weakness F 47 3 weeks
15 1X day
12/3/2020
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 1  Insomnia Restless legs at night, nausea , headache, bad bloated painful stomach, lower back pain , lethargic, acid reflux, jittery internal shaky feeling, unable to control temperature going from hot to cold , bad weight gain Did not do anything for insomnia literally made me feel more wired just could not relax , my stomach felt so bad at 6 weeks I could no longer continue I felt like I had flu as well, I tapered down to 7.5 mg for a week then came off but a warning to anyone taking it even after a short time of 6 weeks on this the withdrawal is not pleasant I’ve now got severe ibs type symptoms, I’m 10 days out from quitting and the stomach issues and headaches are brutal hoping it passes soon , did nothing for me wish i had never took it because I am now left with the worst ibs the stomach pain is all day every day praying it is over soon. F 45 6 weeks
15 1X day
11/9/2023
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 3  Sleep Weight gain! Hunger, vivid dreams. Would be a great drug if not for weight gain. F 40 7 weeks
3.75 1X day
3/23/2021
 1  depression extreme aching of legs. unable to think, at all. stopped all! thought. couldn't be depressed on this med, and couldn't be anything. was a lobotomy. i liked it and was SO depressed before i took the med- and was happy to swap the lobotomy for my terrible depression, but i also couldn't walk due to the EXTREME aching in my legs / myalgia, and that was not acceptable to me. one other thing: i was sleeping 20 hrs a day and having the worst nightmares ever. M 48 1 months
1X day
9/25/2017
 3  IBS-D and anxiety Increased appetite, started at 15mg and after 2 weeks symptoms returned. Dosage upped to 30 mg a day and after 1 month symptoms returned. F 35 2 months
30mg 1X day
8/12/2020
 2  Anxiety Lightheaded, insomnia, nausea, bloated painful stomach, acid reflux, flu type aching all over body, headache, heightened anxiety , restless legs at night and feeling agitated and rapid and mean rapid weight gain. I was switched to this from amitriptyline because my anxiety was getting bad and my doctor told me Mertazipine works much better than amitriptyline I was only on 10mg of amitriptyline and had no issues, but my god Mertazipine is the stuff of the devil I had all of the above started having full on panic attacks every time I went to go out it had the opposite effect on sleep and kept me awake feeling restless and irritated, I felt so sick and so dizzy it was unbearable, and the weight gain is unbelievable i gained 1 stone I’m just the 2 months on it , it also took my cholesterol levels very high , I know it works for some but please read the enclosed leaflet that comes with it and do your research I did know about the cholesterol levels being raised but when I questioned my doctor it said it was rare but it happened to me , and how the hell can it be healthy to put someone on a med that causes such terrible weight gain which I’m turn will cause other health issues, and for anyone who says control your diet I didn’t eat anything more while on it and I don’t want to live my life eating lettuce and drinking only water , please be careful if you are given this withdrawal is absolutely brutal after on a short time, I’ve been on several antidepressants over the years and this is absolute hell to be on and even worse to get off, I’m going back to amitriptyline if I survive F 50 2 months
15 1X day
10/24/2023
Email
 1  Anxiety Disorder GAD Bad depression. total despair and lack of motivation or emotional feeling , Light Headedness, unable to function properly and did't care about anything or anyone including myself. This is a really TERRIBLE drug. Was given Mirtazapine because new doctor didn't like prescribing Valium, which I had used most successfully on many occasions, so I agreed to try it - big mistake. Woke up after taking it feeling light headed, unable to function, and totally out of it. I was told it would also help me sleep at night, possibly did for the first few days but it wasn't a refreshing sleep, more like going to sleep and the alarm going off a minute later. I wasn't depressed when I started this medication, however it caused me to be. I would cry for no reason wherever I was, and lost all interest in life almost to the point of wanting to end it. At that point I immediately stopped taking it. It only took a few days to recover from the effects of Mirtazapine probably due to the fact that I hadn't used it for long. I still suffer from the anxiety and panic attacks I have had for most of my life but they are not as bad as the effects of Mirtazapine. The depression etc, disappeared after I stopped this drug, so I knew it was Mirtazapine that had caused my other problems. For me, this has been the most dangerous drug I have ever taken in more than fifty years of having anxiety problems. IN MY OPINION DO NOT TAKE IT OR BE CAREFUL AND STOP IT IF YOU START TO GET DEPRESSED F 69 2 months
15 1X day
10/6/2020
 1  Anxiety and depression Could not stay awake, always felt hungover. Didn't help with anxiety or depression. Weight gain. F 43 3 months
15 mg 1X day
12/8/2021
 4  Depression, Insomnia Slight increase in appetite, some very vivid dreams (pretty cool not gonna lie) Definitely helped me have deeper sleep. Can't say it affected my depression too much as I was on the lowest dose. M 20 8 months
15 MG
5/15/2020
 3  Anxiety and depression I suffer from insomnia and mirtazapine really helps. It took around 3 weeks to help with the anxiety/depression. I would be happy to stay on them but for the bloating and weight gain. I don't usually have a weight problem but both times I have been on it my weight has rocketed. I have also become pre-diabetic both times. I am not eating any more that normal but the weight gain starts straight away. Most medication gives me bad side effects and apart from the tiredness, fidgety legs and weight gain, mirtazapine suits me. I would therefore use it again in the future, as I have not been able to find another drug that works as well for me. F 69 9 months
15 1X day
2/20/2021
 1  Insomnia anxiety Not help with anxiety and little sleep.weght gain constipation Suicide ideation F 63 0 years
15 1X day
4/7/2021
Email
 5  Depression, sleeplessness, anxiety bad dreams first night, increased appetite I had been unable to sleep for over a week, just about 15 minutes per night, falling apart. My doctor prescribed 15mg (1/2 tab) of mirtazapine 1 hour before sleep. First night 4-5 hours sleep, but bad dreams. From there 6-8 hours good sleep each night, normal dreams. Fairly rapid lifting of depression (over 1-3 weeks) After 1 year stopped without any effects. Also found meditation (TM) beneficial - would not have done as well on the medication alone. M 68 1 years
15 MG 1X day
3/6/2019
 4  Anxiety, insomnia, mood swings My only side effect was increases appetite that's why I stopped taking it gradually. Apart from that it's a great medicine, I liked its calming effect, took at a night time, didn't make me drowsy or tired next day. Give it few weeks F 29 1 years
30 1X day
12/11/2021
 3  GAD/Social Phobia/Panic Attacks Extreme hunger and loss of libido. Hunger and appetite problems can be conquered with lots of effort. Libido issue after a year hasn't improved. Sometimes normal desires can occur which is welcome when it happens. Great for getting to sleep. Some vivid dreams, nothing that creates a problem I'd give this medication about a 3.5 if rating system permitted. I average about 75 mg/wk. I tried averaging about 63mg/wk but that caused stress levels to be intolerable. It seems to be better for panic attacks vs. GAD issues. Have a little too much stress but can't tolerate a higher dose. The amount of side effects and their intensity vs. the benefits causes me to want to keep searching for a better solution. Have tried taking a little gabapentin (100mg as needed) with this which may have some positive results. After taking antidepressants for 20 years I suffer from a little depression or I've developed a need/dependency for the drug class. Mirtaz does not seem to offer the mood lift that I need. I was hopeful that the sexual side might not be too severe but the libido issue is not good although ability is not bad. I continue to search for that best mix that until now remains elusive. I started this drug a year ago when I was 56. I'm not giving up on it yet. I'll likely try some other combinations. I had a bad serotonin syndrome hit which can really cause you to begin to doubt all the drugs and made me fearful of not finding something I can live with. So I want to be more patient. I tried a number of combinations with Nefazodone as the primary med. Nefaz did not seem to want to cooperate with other meds and led to the brick wall I hit before switching to Mirtaz. I tried taking brand Remeron but to me there was not detectable difference. M 57 1 years
Apx 10.7mg 7X W
6/18/2019
 2  Severe depression Bloating, stomach pains, severe diarrhoea and occasional vomiting, constipation I only continue to take this drug because I became severely depressed to feeling suicidal, I feel I have benefited from taking it but the stomach problems are horrendous! Nausea is awful too. I sleep better but wake up feeling as though I've not slept. I would love to wean off it but I'm scared to, I have tried but was very Ill. F 65 1 years
30mg 1X day
7/8/2022
Email
 5  depression Sleepiness weight gain I F 25 2 years
15 mg
10/4/2014
Email
 2  Anxiety/ Depression Felt like I was always on the edge. Felt restless and panicked. Do not recommend. Beware. F 49 2 years
7.5 1X day
5/20/2021
Email
 5  treatment resistant depression I suffered all my life with treatment resistant depression. I was already taking Parnate 90mg a day and the addition of mirtazapine worked wonders for me. I have never been happier M 57 4 years
60 1X day
11/16/2016

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